Specific oral tolerance induction in childhood
نویسندگان
چکیده
منابع مشابه
Specific oral tolerance induction in food allergy.
Specific oral tolerance in food allergy can be induced by oral administration of the offending food, starting with very low dosages, gradually increasing the daily dosage up to an amount equivalent to a usually relevant dose for daily intake, followed up by a daily maintenance dose. Unfortunately, the body of scientific evidence concerning specific oral tolerance induction (SOTI) is still rathe...
متن کاملAdverse effects during specific oral tolerance induction: in home phase.
BACKGROUND Specific oral tolerance induction (SOTI) is a promising approach for severe food allergies. There are little data in the literature regarding the home-phase of SOTI, not only with regard to type and frequency of adverse reactions but also regarding the most suitable treatment and protocol. AIMS To define the incidence and severity of adverse reactions, possible risk factors, and th...
متن کاملSpecific oral tolerance induction for food. A systematic review.
BACKGROUND Specific oral tolerance induction (SOTI) is a new therapeutic approach in the treatment of persistent food allergy. OBJECTIVE The purpose of this article is to systematically review the literature in order to identify, appraise, and synthesize the evidence about SOTI efficacy and safety. METHODS A comprehensive search for citations was conducted on May 2, 2009 using MEDLINE via P...
متن کاملSpecific Oral Tolerance Induction in Food Allergy in Children: Efficacy and Clinical Patterns of Reaction
who underwent OFCs at the Duke University pediatric allergy-immunology clinic, excluding patients with a history of severe symptoms with previous reactions, were studied. Patient-selection criteria were based on the clinical history, results of skin-prick tests, and foodspecific immunoglobulin E (IgE) levels that were much lower than those previously published levels predictive of a high likeli...
متن کاملSpecific oral tolerance induction in food allergy in children: efficacy and clinical patterns of reaction.
BACKGROUND Specific oral tolerance induction (SOTI) seems to be a promising treatment of food allergy. Specific oral tolerance induction and elimination diet were compared with respect to efficacy rate and patterns of clinical reaction. METHODS Children with challenge proven immunoglobulin E (IgE)-mediated cow's milk (CM) allergy or hen's egg (HE) allergy were randomly assigned to SOTI or eli...
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ژورنال
عنوان ژورنال: Pediatric Allergy and Immunology
سال: 2016
ISSN: 0905-6157
DOI: 10.1111/pai.12620